We are pleased and proud to present our new camera for hyperspectral imaging, the TIVITA® 2.0.
After intensive development work and extensive testing, the TIVITA® 2.0 has successfully passed the conformity assessment procedure and is now available. If you are interested, please contact our sales partners or us directly.
Once again, a working group from the University of Leipzig was able to demonstrate the high potential of TIVITA . This study on the monitoring of free flap grafts illustrates that HSI technology provides reliable data for monitoring perfusion and oxygenation of the flaps, detects complications at an early stage and is far superior to other techniques.
Source: Kohler LH, et al. Hyperspectral Imaging (HSI) as a new diagnostic tool in free flap monitoring for soft tissue reconstruction: a proof of concept study. BMC Surg. 2021 Apr 30;21(1):222. doi: 10.1186/s12893-021-01232-0
https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-021-01232-0
In addition, a second publication by Mühle et al. appeared, which describes the integration of HSI into the intraoperative neurosurgical workflow and gives hope for the future that HSI can also provide assistance in this specialty. The main focus here is on tumour detection and the determination of resection margins.
Source: Mühle R, et al. Workflow and hardware for intraoperative hyperspectral data acquisition in neurosurgery. Biomed Tech (Berl). 2020 Jul 25. doi: 10.1515/bmt-2019-0333
https://www.degruyter.com/document/doi/10.1515/bmt-2019-0333/html
We would like to thank all participants for their great work!
We are pleased about the funding of the project "MultiGuard", which we will work on in cooperation with the Innovation Center Computer Assisted Surgery (ICCAS) of the University of Leipzig.
The aim of the project is to develop a clinically applicable multispectral camera system for intensive monitoring in adult and neonatal intensive care units. The monitoring system will be used to continuously monitor tissue perfusion and hydration during volume therapy and ventilation to prevent complications.
In an observational study at Heidelberg University Hospital, in collaboration with Essen University Hospital, it was demonstrated for the first time that TIVITA® is a promising tool for visualizing microcirculatory oxygenation and perfusion parameters of the skin in critically ill people. The unique ability to easily and quickly image water tissue content using HSI technology may additionally provide new insights for fluid therapy.
We thank the working groups for this groundbreaking work and look forward to further cooperation!
At the end of February 2021, we had the opportunity to test the TIVITA Mini Endoscopy Edition together with Professor Michele Diana and Doctor Lorenzo Cinelli under real operating conditions. The two surgeons from IRCAD in Strasbourg tested the functionality of the TIVITA Mini in endoscopic use in an experimental setting. The results were very satisfactory and point to a new milestone in medical diagnostics. All planned functions of the endoscopic HSI camera could be successfully demonstrated and all present were convinced that we are on the right track to establish HSI for endoscopic use.
We would like to thank all participants for this opportunity, our special thanks go to the whole team of IRCAD!
In cooperation with IRCAD in Strasbourg, new ways of diagnostics in medicine are repeatedly demonstrated at the University Medical Center Leipzig.
In a recent publication in "Cancers", Jansen-Winkeln et al. were able to show for the first time that it is possible to detect and classify colorectal cancer tissue by combining HSI and artificial intelligence. Based on a neural network, tumor classification resulted in a sensitivity of 86% and a specificity of 95%. Similarly, significant differences in perfusion parameters (e.g. oxygen saturation) depending on tumor stage and neoadjuvant therapy were observed using TIVITA®.
This once again impressively demonstrated what HSI is capable of. We are pleased to be able to make a valuable contribution to medical diagnostics with the TIVITA and thank the authors for the helpful publication.
In a recent publication on a prospective study, HSI was shown to help monitor transplanted tissue and support decision making on the right therapy.
Furthermore, a treatment algorithm was demonstrated that allows a fast and reliable perfusion assessment and conclusions about the origin of reduced perfusion based on the TIVITA data.
We are delighted with this very good work and are once again reaffirmed that our technology can have a decisive influence on improved medical care, especially as the evidence for this continues to grow. Many thanks to the working group from Halle.
We are pleased about the funding of our R&D single project "EMMA" by the state and the European Fund for Regional Development and thank TBI Technologie-Beratungs-Institut GmbH for their support!
This project aims to develop a miniaturized multispectral imaging system for optimal assessment of tissue perfusion and more precise visualization and monitoring of relevant structures for minimally invasive surgery.
This project is co-financed by the European Union from the European Regional Development Fund.
Users are thus provided with additional diagnosis-supporting information that is not visible to the human eye. By expanding the surgeon's field of view and assisting in the detection of anatomical risk structures and pathological changes, the clinical outcome for patients during complex operations can potentially be improved.
The basis for the development of the TIVITA® Mini is the TIVITA® Tissue, which has already established the technology of hyperspectral imaging for open surgical applications, among others, and is successfully used intraoperatively, e.g. for the assessment of anastomoses and for the precise determination of resection positions.
The TIVITA® Mini can be used in all specialties in which minimally invasive surgery is used, for example, in the..:
The TIVITA® Mini is offered as a complete system consisting of the core components: endoscopic HD camera for live video and HSI recordings, imaging centre (broadband LED illumination unit, powerful computer) including application software, two monitors, endoscopic optics and optionally with equipment trolley and foot switch.
Thanks to different camera sensors, it is possible to permanently see a colour video and simultaneously take any number of HSI images, which are displayed on the second monitor. With only one hyperspectral image by the TIVITA® Mini, various blood flow and substance parameters are shown to you. These include:
Several studies compare hyperspectral imaging with ICG fluorescence imaging technique for intraoperative perfusion monitoring. Studies to date clearly show that HSI and FI-ICG are comparable imaging techniques, are reliable predictors of adequate perfusion and can be used in a complementary manner.
Compared to HSI, fluorescence-based technologies are associated with some risks for the patients, since, in contrast to non-invasive HSI, the injection of a fluorescent dye is necessary. Phototoxic effects and hypersensitivity reactions have been described. It is also disadvantageous that inflammatory changes, abscesses and necrotic areas result in false positive fluorescence. In addition, the quality of the signal is strongly dependent on the type of tissue and can also be negatively influenced by the effect of "photo-bleaching".
In addition, the use of the TIVITA® Mini System is more cost-effective, as the material input of 25 mg ICG alone costs approximately €80 [Baiocchi GL, Diana M, Boni L. Indocyanine green-based fluorescence imaging in visceral and hepatobiliary and pancreatic surgery: State of the art and future directions. World journal of gastroenterology, 2018, Vol. 24, No. 27, p. 2921] - these ongoing costs are completely eliminated for HSI. This saving is equivalent to a value of €80,000-€240,000 over five years, assuming one to three missions per day for 200 working days per year. Further advantages of HSI are the short preparation and measurement time, reproducibility and repeatability of the images, independent of the distribution of a dye in the organism.
Here you will find your distributor and a list of important literature.
The TIVITA® 2.0 Surgery Edition can be used in the following specialties, for example:
The TIVITA® 2.0 Surgery Edition is offered as a system consisting of the core components: HSI/RGB camera including gimbal and support arm, broadband LED illumination source, computer including software and two full HD monitors. In addition, a medical trolley as well as a handle adapter for sterile disposable drapes and a wired foot switch are available.
With just one hyperspectral image through the TIVITA® 2.0, you are presented with various blood flow and substance parameters. These include:
The TIVITA® 2.0 Surgery Edition is offered as a system consisting of the core components: HSI/RGB camera including gimbal and support arm, broadband LED illumination source, computer including specialized surgery software and two full HD monitors. Further components are: medical trolley, handle adapter for sterile disposable drapes and wired foot switch.
Here you will find a list of important literature.